20/09/2019
Marie Skłodowska-Curie Actions

PhD student – Early Stage Researcher: Development of diabetes-sensitive computational models of bone strength for the clinical diagnosis and pre-clinical tracking of diabetic bone fragility


  • ORGANISATION/COMPANY
    Universitaetsklinikum Hamburg-Eppendorf (UKE)
  • RESEARCH FIELD
    Biological sciencesBiological engineering
    Computer scienceInformatics
    Computer scienceOther
    EngineeringBiomedical engineering
    EngineeringMechanical engineering
  • RESEARCHER PROFILE
    First Stage Researcher (R1)
  • APPLICATION DEADLINE
    20/10/2019 21:00 - Europe/London
  • LOCATION
    Germany › Hamburg
  • TYPE OF CONTRACT
    Temporary
  • JOB STATUS
    Full-time
  • HOURS PER WEEK
    40
  • OFFER STARTING DATE
    01/01/2020
  • EU RESEARCH FRAMEWORK PROGRAMME
    H2020 / Marie Skłodowska-Curie Actions
  • MARIE CURIE GRANT AGREEMENT NUMBER
    860898

The EU-funded Innovative Training Network FIDELIO (https://www.fidelio-project.eu) aims to train the next generation of scientists in order to tackle the challenges of diabetic bone disease from various angles and with the newest technologies available. Interdisciplinary training and implementation of innovative approaches are key. Within this consortium, we will comprehensively unravel the genetic and environmental mechanisms that contribute to bone fragility in diabetes, identify predictors and clinical markers for patient stratification, decipher the underlying molecular mechanisms of bone fragility in diabetes, and establish potential interventions through a personalised medicine approach.
The research programme will address different aspects of diabetic bone disease from the viewpoints of epidemiology, genetics, miRNAs, microbiome, bone biology, bone biomechanics and microstructure, preclinical and clinical research. It will utilise advanced imaging and computational approaches, diabetes mouse models and access to clinical cohorts and registry data to obtain a comprehensive overview of how these mechanisms combine in diabetes to cause increased fracture risk.
With this interdisciplinary approach, we can explore the impact of biological pathways in mouse models and/or humans, and interactions with diet, exercise and other exposures.
Collaborations with industry will allow early identification of IP, access to state of the art technologies, and will complement the academic ESR training programme with entrepreneurship and industrial mentoring.

Benefits

· You will be working within our international, interdisciplinary team of >30 researchers with experience in a broad range of sciences.
· You will get in contact with the other members of this international consortium and will benefit from the joint training platform to develop skills necessary for developing a thorough understanding of the mechanisms of diabetes and the bone metabolism and for obtaining industry skills.
 
· You will be employed by the host organization for 36 months.
· A competitive salary plus allowances. Moreover, funding is available for technical and personal skills training and participation in international research events.
· You will benefit from the designed training program offered by the host organization and the consortium.
· You will participate in international conferences and secondments to other organizations within the FIDELIO network and in outreach activities targeted at a wide audience 
 
Please find additional information in the Information package for Marie Curie fellows

Selection process

Planned key dates:
25 November 2019: Recruitment event in Rome, Italy

Web site for additional job details

Offer Requirements

  • REQUIRED LANGUAGES
    ENGLISH: Excellent

Skills/Qualifications

· Applicants must hold an MSc or equivalent in the field of biomedical engineering, biomechanical engineering, bioinformatics, computer sciences or a related program
· Applicants must have knowledge and/or experience in finite element modelling
· Willingness to work with bone specimens from animals and humans is a prerequisite
· Applicants can be of any nationality
· Applicants must have an ability to understand and express themselves in both written and spoken English to a level that is sufficiently high for them to derive the full benefit from the network training
· Applicants must be eligible to enroll on a PhD program at the host institution (or a designated university in case the host institution is a non-academic organization)
 
In addition:
H2020 MSCA Mobility Rule: researchers must not have resided or carried out their main activity (work, studies, etc.) in the country of the host organization (Germany) for more than 12 months in the 3 years immediately before the recruitment date. Compulsory national
service, short stays such as holidays, and time spent as part of a procedure for obtaining refugee status are not taken into account.
Eligible researchers must not have spent more than 12 months in the 3 years immediately prior to the date of selection in the same appointing international organisation.
H2020 MSCA eligibility criteria: Early Stage Researchers (ESRs) must, at the date of recruitment by the host organization, be in the first four years (full-time equivalent research experience) of their research careers and have not been awarded a doctoral degree. Full-Time Equivalent Research Experience is measured from the date when the researcher obtained the degree entitling him/her to embark on a doctorate (either in the country in which the degree was obtained or in the country in which the researcher is recruited, even if a doctorate was never started or envisaged).

Map Information

Job Work Location Personal Assistance locations
Work location(s)
2 position(s) available at
Heisenberg Research Group (Busse lab)
Germany
Hamburg

EURAXESS offer ID: 447770

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